Introduction to the basic concepts of pharmacology. Mechanisms of action of antibacterial, antiviral, antifungal and anticancer drugs, toxins and how cellular resistance to such agents develop. Applications of drug-resistant mutants for genetic, biochemical pharmacological and cell biological studies. Three lectures; first term Prerequisite(s): BIOCHEM 2BB3; or BIOCHEM 2EE3 (or LIFE SCI 2EE3) and BIOCHEM 3G03; or HTH SCI 2E03; or ISCI 2A18